Hospital tests

12) Mannitol Challenge Test

Mannitol challenge test

Mannitol challenge test

For the mannitol challenge test:

  • You will have resting Spirometry measured before starting the challenge.
  • You will be asked to breathe in powder from an inhaler, and asked to hold your breath for 5 seconds before breathing out.
  • The Spirometry test will be repeated after 1 minute.
  • This is repeated with the amount of powder you breathe in being doubled each time. Spirometry is repeated after each increased dose to check how the airways are working.
  • Once the maximum dose has been given or there is a deterioration in your breathing, the test will be stopped.
  • If your breathing  is worse before the maximum dose has been reached, a nebuliser will be given to relieve any symptoms. You will be supervised by a physiologist during and after this test.